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End Chronic Stomach Problems!

Natural Solutions to Chronic Stomach Problems

The stomach is protected by a thick coating of mucus that is steadily secreted by the surface mucous cells in the stomach's lining. An estimated 20 million Americans suffer stomach discomfort and stomach pain caused by erosion of that protective mucosal lining. A healthy mucosal lining is required to prevent acidic digestive juices from corroding the stomach wall.

The Helicobacter pylori (H. pylori) bacterium is yet another enemy of the stomach lining. H. pylori exerts pro-inflammatory effects in stomach tissue, further exacerbating stomach problems.

Protecting against known factors that damage the gastric lining is essential to ensuring optimal stomach health.  Now there is a product called Gastro-Easeā„¢ that combines two remarkable nutrient compounds that naturally inhibit the growth and damaging effects of H. pylori while protecting and restoring the health of the gastric lining.

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Uncovering a healthier remedy for chronic pain

DURHAM, N.C. -- Physicians and patients who are wary of addiction to pain medication and opioids may soon have a healthier and more natural alternative.

A Duke University study revealed that a derivative of DHA (docosahexaenoic acid), a main ingredient of over-the-counter fish oil supplements, can sooth and prevent neuropathic pain caused by injuries to the sensory system. The results appear online in the Annals of Neurology.

The research focused on a compound called neuroprotectin D1=protectin D1 (NPD1=PD1), a bioactive lipid produced by cells in response to external stimuli. NPD1=PD1 is present in human white blood cells, and was first identified based on its ability to resolve abdominal and brain inflammation.

"These compounds are derived from omega-3 fatty acids found in fish oil, but are 1,000 times more potent than their precursors in reducing inflammation," said Ru-Rong Ji, professor of anesthesiology and neurobiology at Duke University Medical Center and principal investigator of the study.

The team used laboratory mouse models of nerve injuries to simulate pain symptoms commonly associated with post-surgical nerve trauma. They treated these animals with chemically-synthesized NPD1=PD1, either through local administration or injection, to investigate whether the lipid compound could relieve these symptoms.

Their findings revealed that NPD1=PD1 not only alleviate
On the other hand, NPD1=PD1 can relieve neuropathic pain at very low doses and, more importantly, mice receiving the treatment did not show signs of physical dependence or enhanced tolerance toward the lipid compound.

"We hope to test this compound in clinical trials," Ji said. The initial stages of the trial could involve DHA administration through diet and injection. "DHA is very inexpensive, and can be converted to NPD1 by an aspirin-triggered pathway," he said. The ultimate goal is to develop a safer approach to managing chronic pain.
How Protectin D1 Works
How Protectin D1 Works
A compound derived from the DHA in fish oil -- Protectin D1 (PD1/NPD1) -- offers protection from nerve trauma-induced neuropathic pain by preventing neuronal and glial hyperactivity in the spinal cord. Glial cells, when activated, produce proinflammatory cytokines that may further damage the nerve cells.
(Credit: Ru-Rong Ji and Zhen-Zhong Xu, Duke University Medical Center)
Story Source:
The above story is reprinted from materials provided by Duke University, via EurekAlert!, a service of AAAS.

Acid Reflux Drug May Cause Heart Disease, According to Study

July 19, 2013 -- Drugs prescribed to millions of people to cope with acid reflux may also cause cardiovascular disease, report scientists from Houston Methodist Hospital and two other institutions.

Proton pump inhibitors, such as Prilosec, Prevacid and Nexium, are used to treat a wide range of stomach disorders, most notably gastroesophageal acid reflux, or severe heartburn. Available both over the counter and with a prescription, they are the third highest-selling class of drugs in the United States.

"The surprising effect that PPIs may impair vascular health needs further investigation," said John Cooke, M.D., Ph.D., the study's principal investigator. "Our work is consistent with previous reports that PPIs may increase the risk of a second heart attack in people that have been hospitalized with an acute coronary syndrome. Patients taking PPIs may wish to speak to their doctors about switching to another drug to protect their stomachs, if they are at risk for a heart attack."
Story Source:
The above story is from materials provided by Methodist Hospital, Houston.